CD40LG and coronary artery disorder: Anti-oxLDL antibodies of the IgM subclass have been generally found to confer protective benefit from coronary artery disease (CAD) and CVD, and indeed lower levels of IgM to one well-characterised epitope [malondialdehyde-modification of LDL (MDA-LDL)] have been linked with features of atherosclerotic plaques vulnerable to rupture (5).