Previous studies have reported that four AQP family members (AQP1, AQP 3, AQP 4, and AQP 5) were expressed in lung tissues (Warth et al., 2011; Verkman, 2012; Wittekindt and Dietl, 2019); therefore, we further explored the expression levels of these genes with different tumor stages for LUAD patients using UALCAN databases. The gene discussed is AQP1; the disease is neoplasm.