lncRNA PVT1 (plasmacytoma variant translocation 1) and SCUBE2 (signal peptide-CUB-EGF-like containing protein 2) were upregulated, whereas miR-543 was downregulated in synovial tissues of RA rats and patients (Wang et al., 2020). The gene discussed is PVT1; the disease is rheumatoid arthritis.