BCAR1 and breast neoplasm: In human breast tumors, high levels of p130Cas expression correlates with a poor response to tamoxifen therapy, quicker disease recurrence and decreased patient survival (Dorssers et al., 2001), suggesting that p130Cas/BCAR1 expression might be a convenient prognostic marker for patients affected by primary or metastatic breast cancer (van der Flier et al., 2000; Table 1).