Oncomine database analysis showed that HK2 expression in bladder (Sanchez-Carbayo et al., 2006), brain and CNS (Bredel et al., 2005; French et al., 2005; Murat et al., 2008; Sun et al., 2006), esophageal (Hao et al., 2006), gastric (D’Errico et al., 2009), head and neck (Vasko et al., 2007), kidney (Jones et al., 2005; Gumz et al., 2007; Beroukhim et al., 2009), ovarian (Yoshihara et al., 2009), and pancreatic adenocarcinoma (Iacobuzio-Donahue et al., 2003; Badea et al., 2008; Pei et al., 2009) was higher than that in normal tissue samples. This evidence concerns the gene HK2 and pancreatic adenocarcinoma.