MKI67 and neoplasm: We used ROC curves to derive optimal cutoff values for age (51 years, AUC=0.597, 95% CI 1.17–3.26), tumor size (4.2 cm, AUC=0.638, 95% CI 1.65–4.70), and Ki-67 index (10%, AUC=0.659, 95% CI 1.55–4.17).