Therefore, AGGstimulates p73 and suppresses the EGF-induced EMT and invasiveness byinhibiting the ERK/Snail pathway [128].Protoporphyrin IX (PpIX), a metabolite of aminolevulinic acid, which is used inphotodynamic cancer therapy, stabilizes TAp73 and activates TAp73-dependentapoptosis in tumor cells lacking p53. The gene discussed is TP53; the disease is cancer.