TP53 and neoplasm: Furthermore, the low-molecular-weight agentsVIP116 and PM2 inhibiting the p53-Mdm2 and p53-Mdm4 interactions, which weredelivered inside lipodisks (the nanosized bilayer structures stabilized intoflat circular shapes by lipids linked to polyethylene glycol), significantlyreduced the viability of tumor cells [136].