HACE1 is also downregulated in natural killer/T-cell lymphoma of the nasal type (NKTCL) (Huang et al., 2010), colorectal cancer (Hibi et al., 2008) and gastric cancer (Sakata et al., 2009). The gene discussed is TNFRSF10B; the disease is extranodal nasal NK/T cell lymphoma.