APLN and in situ carcinoma: According to ROC-based analysis, Apelin <2.262 ng/mL at T2 had a sensitivity of 70.00% and a specificity of 83.00% in forecasting death of CIS patients with HT after thrombolysis (all P < 0.001), and Vaspin <1.240 ng/mL at T2 had a sensitivity of 70.00% and a specificity of 86.11% in forecasting it (all P < 0.001).