ANGPTL4 and type 1 diabetes mellitus: Additionally, the Mg-regulated network comprised of pathways related to post-translational protein phosphorylation (VWA1-upregulated), Type I diabetes mellitus (PTPRRN- and HLA-DQB1-upregulated), endocrine resistance (BIK-upregulated), and regulation of lipid metabolism by PPAR-alpha (ANGPTL4-upregulated) (Figure 7A).