PTGS2 and ischemic stroke: The expression of three other ferroptosis-related biomarkers, PTGS2, MAP1LC3B, and TLR4, was all upregulated in ischemic stroke patients vs. normal control in the GSE16561 (Figure 4A, all p < 0.05) and GSE140275 datasets (Figure 4B, all p < 0.05).