CD32b, together with stabilin-1, stabilin-2, and lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), were sequentially lost during tumor progression in mice with inducible HCC (AST model), as well as in human HCC patients (examined in tissue microarrays) (Geraud et al., 2013). This evidence concerns the gene LYVE1 and hepatocellular carcinoma.