CLEC4M and COVID-19: Recently, human L-SIGN was shown to act as a receptor for SARS-CoV-2 (Kondo et al., 2021) and the hypothesis was presented that L-SIGN mediated SARS-CoV-2 infection in LSECs, and subsequent activation of the sinusoidal endothelium contributes to COVID-19-associated coagulopathy in patients.