INS and Hypoglycemia: This subpopulation of type 1 diabetic patients refers to those who are extremely sensitive to insulin and lack counter-regulatory measures, increasing their risk of neuroglycopenia (abnormally low glucose level in brain) with hypoglycemia unawareness (diabetic complication in which patient is unaware of hypoglycemia and its characteristic symptoms), severe hypoglycemic episodes and glycemic lability (swing in blood glucose from high to low and vice versa) (Shapiro et al., 2017; Rickels and Robertshon, 2019).