In addition to this parameter, we also showed that sVCAM, NOX2, NOX4, and iNOS expression, as well as ROS production, vascular remodeling, cellular infiltration, fibrosis, mesangial expansion, and liver inflammation increased after AGII intraperitoneal administration, along with the concentration of TNFα, IFNγ, IL1β, VCAM-1, ICAM-1 and TGFβ. This evidence concerns the gene TNF and medical procedure.