After recovering from a first AKI episode, the urinary excretion of transferrin, IGFBP7, TIMP-2 and IGFBP7*TIMP-2 is significantly higher in rats predisposed to suffer new AKI episodes (R0, R1) than in those who do not present this predisposition (R2) (Fig. 7b–e), while there are no changes in urinary albumin excretion in rats predisposed to a new AKI (Fig. 7a). This evidence concerns the gene IGFBP7 and acute kidney injury.