INS and type 2 diabetes mellitus: The patients without T2DM remission could have low levels of magnesium due to longer diabetes duration and a more deteriorated glucometabolic status, which can contribute do lower T2DM remission (30), however, we know that magnesium has an important role in the insulin action (18) and although these factors may have influenced them, they will certainly not be the only explanation of the observed data.