In addition, Kaplan–Meier Plotter analysis (http://www.kmplot.com) showed that high-C1QB (Complement C1q subcomponent subunit B) and low-C1INH (C1-inh, C1 esterase inhibitor) are correlated with poor distant metastasis-free survival in the breast cancer samples (Supplementary Fig. 7A). Here, SERPING1 is linked to breast cancer.