Further comparison of IGF2PB2 expression between AD and normal samples in three data sets (GSE33000, GSE48350 and GSE5281) also showed that IGF2BP2 expressed more in AD patients than in normal people (GSE33000: log2FoldChange = 0.170, p<2.22e-16, Figure 1B; GSE48350 and GSE5281: log2FoldChange = 1.488, p=1e-11, Figure 1C). Here, IGF2BP2 is linked to Alzheimer disease.