NLRP3 and colitis: Similar to P. mirabilis, the lack of NLRP3 or the blockade of IL‐1 signaling cancels the colitogenic effect of K. aerogenes, suggesting the central role of the NLRP3–IL‐1β axis in the pathogenesis of oral commensal pathobiont‐driven colitis (Kitamoto et al, 2020).