Herein, the levels of lncRNA KCNQ1OT1, miR-296-5p and HYOU1 in clinical tumor tissue specimens and CC cell lines were assessed and the influences of lncRNA KCNQ1OT1/miR-296-5p/HYOU1 on CC cell proliferation, migration, invasion as well as tumor growth were evaluated, so as to determine the specific role of lncRNA KCNQ1OT1 and explore the molecular mechanism underlying the participation of KCNQ1OT1 in the development of CC. Here, HYOU1 is linked to neoplasm.