We observed noteworthy associations such as links between LRP8 and psychological traits, SORT1 and cholesterol metabolism, KCNK3 and hypertension and obesity, NEK10 and cardiovascular traits, HTT and platelet count, alcohol intake, socio‐economic status and obesity, POM121C and obesity, CCDC71L and platelet count and hypertension, NRG1 and height, RAD52 and basal metabolic rate and obesity, CHRNA2/3/4/5 and smoking behavior and lung phenotypes, FURIN/FES and cardiovascular traits, HP and lipid and hemoglobin concentrations as well as BECN1 and abdominal obesity. The gene discussed is LRP8; the disease is obesity due to melanocortin 4 receptor deficiency.