TNFRSF1A and endothelial dysfunction: In addition, the adipocyte-derived exosomal lncRNA SNHG9 can directly bind to the tumor necrosis factor receptor 1 (TNFR1)-associated death domain protein (TRADD) mRNAs, which, thus, constituted an RNA dimeric inducible-silencing complex and reduced endothelial dysfunction of obese patients.75