Using univariate analysis, increasing age (P < 0.001), hypertension (HTN) (P = 0.001), the use of angiotensin converting enzyme inhibitors (ACEI)/angiotensin II receptor blockers (ARBs) (P = 0.005), APACHE II score (12.2 (SD ± 4.1) for the AKI group vs. 10.7 (SD ± 3.8) for the non-AKI group ( P = 0.0001)), and serum albumin at admission (mean serum albumin for the AKI group was 30.1 g/l (SD ± 9.4) and 33.5 g/l (SD ± 8.9) for the non-AKI group (P = 0.001)) were predictors of AKI (Table 3). This evidence concerns the gene ACE and acute kidney injury.