FERMT3 and COVID-19: As an essential integrin activator,18 the presence of kindlin-3 in neutrophils also negatively regulates NET release, which can subsequently suppress venous thrombosis in mice, as demonstrated in our previous studies.19,36 Therefore, we hypothesized that the elevated expression of kindlin-3 in myeloid cells found in MSC-treated COVID-19 patients might help restrict NET release and thereby reduce the risk of venous thrombosis.