PDCD1 and neoplasm: The authors showed that tumor-associated macrophage (TAM) deprived tumor-infiltrating CD8+ T cells of anti-mouse PD-1 antibody (29F.1A12) on the surface, and that the blocking of mouse FcγRs by specific neutralizing antibodies (2.4G2) induced strong rejection of MC38, a colon adenocarcinoma, in a mouse model50.