Additionally, the lowest muscle strength group was associated with a higher OR for silent lacunar infarcts even with adjustment for insulin sensitivity and other parameters in model 3 (High, 1.00 [reference]; Medium, 1.40 [95% CI 0.98–2.02]; Low: 1.49 [95% CI 1.04–2.15], p for trend 0.037). This evidence concerns the gene INS and infarction.