CXCR4 and Miyoshi myopathy: A recent study by Nabissi et al. [84] found a synergistic effect between Δ [9]-tetrahydrocannabinol, cannabidiol, and cytotoxic agent carfilzomib, resulting in strong anti-cancer activity; it reduced MM cell viability by inducing autophagic-cell death and inhibited MM cell migration by down-regulating expression of chemokine receptor CXCR4 and the CD147 plasma membrane glycoprotein.