IFNAR1 and diabetes mellitus: We performed flow cytometry and transcriptional analysis of splenocytes collected from LEW.1WR1 rats prior to the onset of insulitis and autoimmune diabetes under four conditions: WT without virus (no disease), Ifnar1−/− without virus (no disease), WT with KRV (diabetes), and Ifnar1−/− with KRV (reduced incidence of diabetes).