WNT5A promotes multiple proinvasive features of melanoma cells such as EMT-like process, invasion, metastasis, cell proliferation, and ECM remodeling by melanoma cells (Dissanayake et al., 2008; Dissanayake et al., 2007; Fernández et al., 2016; Lai et al., 2012). Here, WNT5A is linked to melanoma.