A375 and A2058 are human melanoma cell lines carrying BRAF V600E mutations that are broadly used to study WNT5A role in melanoma (Anastas et al., 2014; Connacher et al., 2017; Da Forno et al., 2008; Ekström et al., 2014; Linnskog et al., 2016; Liu et al., 2018). The gene discussed is WNT5A; the disease is melanoma.