In model 2, diabetes duration (AOR 1.13, p  =  0.008), abdominal obesity (24.5, p  =  0.004), depression (AOR 22.1, p  =  0.006), and MMP-14 (per ng/mL) (AOR 1.01, p  =  0.005), were associated with CVD. This evidence concerns the gene MMP14 and major depressive disorder.