Shown in Fig. 4, the high expression of genes CP, LURAP1L and AKR1C1 is strongly associated with poor prognosis in NSCLC (P < 0.05), especially the gene AKR1C1 (P = 0.019) whose low expression dictated a prolonged survival time. The gene discussed is AKR1C1; the disease is non-small cell lung carcinoma.