Moreover, CTHRC1 overexpression was linked to poor OS prognosis for patients with ACC (P = 0.00039), BLCA (P = 0.045), COAD (P = 0.018), KIRP (P = 0.029), LGG (P = 0.015), LIHC (P = 0.0094), MESO (P = 0.025) and SARC (P = 0.0059) within TCGA cohorts (Additional file 5: Fig. S5a). Here, CTHRC1 is linked to adrenal cortex carcinoma.