ESR1 and invasive ductal breast carcinoma: Compared with the black, the white and others got a longer survival time (χ2 = 35.071, P < 0.001); The expression of ER, PR, and HER2, histology of invasive ductal carcinoma, married patients, younger age, radiotherapy, and chemotherapy were all protective factors for BC with bone metastasis (P < 0.001).