The genotype distributions of MTHFR C677T (rs1801133), MTHFR A1298C (rs1801131), MTR A2756G (rs1805087) and MTRR A66G (rs1801394) polymorphisms and breast cancer risk are presented in Table 4 (128 cases and 478 controls). This evidence concerns the gene MTRR and breast carcinoma.