Herein, a total of 210 autophagy genes were included in this study, and 11 of them, i.e. CX3CL1, ULK3, CDKN2A, NRG1, ATG4B, GAA, RGS19, DDIT3, GRID1, DAPK1 and SERPINA1 were shown to be survival-related in CRC. This evidence concerns the gene RGS19 and colorectal carcinoma.