Burada F. et al. named several autophagy-related genes in CRC, including LC3, BECN1, ATG5, ATG10, AMBRA1, UVRAG, BCL2, Bif-1, and inflammatory bowel disease susceptibility genes, however, the effects of these focused molecules in CRC is still unclear due to the conflicting results [7]. Here, AMBRA1 is linked to inflammatory bowel disease.