We cannot completely exclude the possibility that such IL-33–ILC2s niches exist in the endometriotic lesion, as further studies using different types of lesions, such as endometriomas, deep infiltrating endometriosis, and superficial peritoneal lesions, must be carried out to shed light on the IL-33 and ILC2 biology within lesions. This evidence concerns the gene IL33 and endometriosis.