To further validate the effect of LINC00998 in AML, we generated stable LINC00998-overexpressed THP-1 cell lines (Figure 2(e)), and found that LINC00998 also inhibited THP-1 cell viability, colony formation and DNA synthesis rate (Figure 2(f–h)). The gene discussed is SMIM30; the disease is acute myeloid leukemia.