In addition, some lncRNAs have been proven to be a key regulator in AML progression, such as ANRIL [28], HOTTIP [29], SATB1-AS1 [30], etc. Further studies are needed to clarify whether these lncRNAs interact with each other to form a huge regulatory network that accurately controls the occurrence and development of AML, and whether several combinations of these lncRNAs can better diagnose and predict AML. Here, CDKN2B-AS1 is linked to acute myeloid leukemia.