TNFSF10 and neoplasm: TRAIL additionally activatesapoptosis in tumor cells by binding to the death receptors (DR4, DR5)on the cell surface.213,339,340 Additionally, coating a hybrid membrane of platelets and leukocyteson commercially available immunomagnetic beads was very effectivein isolating pure CTCs from clinical blood samples collected frombreast cancer patients, demonstrating the possibility of extendingthese CTCs for in vitro applications and their potentialfor use in personalized medicine.99