METTL3 and triple-A syndrome: Mechanistically, the authors showed that higher levels of miR-34a associated with AAA depends on the increased expression of the Methyltransferase-like 3 (METTL3) in VSMCs that is able to enhance miR-34a maturation by promoting N6-methyladenosine (m6A) RNA methylation through the recognition of Digeorge syndrome critical region gene 8.