The biopsy of lymphonode on the neck was positive for CD20, CD79a, PAX‐5, Ki67 (90%+), Bcl‐2, Bcl‐6, CD10, c‐MYC and negative for CD3, CD5, CyclinD1, CD23, CD21, MUM‐1, suggesting DLBCL, GCB subtype. The gene discussed is CR2; the disease is diffuse large B-cell lymphoma.