Congruently, previous reports showed that CD8 T cells cross‐primed by dendritic cells pretreated with the CM of ER‐stressed tumor cells are severely impaired in antigen‐driven clonal expansion by Mahadevan et al (2012) and T cells treated with ascitic fluid of ovarian cancers have reduced IFN‐γ production (Song et al, 2018). Here, CD8A is linked to neoplasm.