Further, in a landmark study of 102 cases of pancreatic neuroendocrine neoplasms subjected to whole-genome sequencing, EWSR1 gene fusions were seen in a small percentage (3%) [27]; these included novel fusions such as BEND2 as well as one case of EWSR1 exon 7–FLI1 exon 6 gene fusion. The gene discussed is BEND2; the disease is pancreatic neuroendocrine neoplasm.