GAS5 and hypertensive disorder: Another experiment, this time with growth arrest-specific 5 (GAS5), an lncRNA expressed mainly in ECs and VSMCs, showed that this lncRNA, by regulating the functions of ECs and VSMCs via signaling by β-catenin, plays a fundamental role in vascular remodeling in hypertension, which is a determining process in the prognosis of the disease [124].