KMT2A and leukemia: Furthermore, MI-2 was shown to inhibit the oncogenic proliferation and to induce apoptosis of four MLL translocation-harboring human leukemia cell lines (by >95% in 12 d at 6 μM), but not of non-MLL leukemia lines Kasumi-1 and HAL-01 (≤16% inhibition at 12 μM) [133].