The results were enriched in Constitutional Mismatch Repair Deficiency Syndrome, Familial Colorectal Cancer Type X, COLORECTAL CANCER, SOMATIC, Malignant genitourinary tract tumor, colorectal cancer, and hereditary nonpolyposis type 1 (Figure 7D), which further indicated that MC1R was associated with the occurrence and development of CRC. This evidence concerns the gene MC1R and colorectal carcinoma.