SLC2A4 and Insulin resistance: Thus, further studies are required to clarify whether or not TXF promotes AMPK phosphorylation in muscle tissues of KK-Ay/Ta mice like that reported in the gastrocnemius muscle of T2D model db/db mice that were administered with daidzein [30] because the increase in the AMPK phosphorylation-GLUT4 translocation axis may work even under the state of insulin resistance, thus leading to an antihyperglycemic effect of TXF.