Meanwhile, TNF‐α (median [IQR]: 47.1 [33.9–57.4] pg/ml vs. 38.6 [29.3–47.1] pg/ml, P < 0.001) (Figure 4E), IL‐1β (median [IQR]: 4.4 [2.5–6.2] pg/ml vs. 2.6 [1.5–4.0] pg/ml, P < 0.001) (Figure 4F), IL‐6 (median [IQR]: 19.2 [14.7–21.7] pg/ml vs. 16.7 [11.8–21.0] pg/ml, P = 0.016) (Figure 4G), and IL‐17 (median [IQR]: 40.0 [31.6–59.0] pg/ml vs. 36.3 [24.8–49.3] pg/ml, P = 0.018) (Figure 4H) were elevated in depression NSCLC survivors compared to non‐depression NSCLC survivors. This evidence concerns the gene TNF and depressive disorder.