Inflammatory cytokines (especially tumor necrosis factor‐α [TNF‐α], interleukin‐1β [IL‐1β], interleukin‐6 [IL‐6], and interleukin‐17 [IL‐17]) have been proposed as modulators for key psychobiological substrates (such as hypothalamic–pituitary–adrenal axis dysregulation and monoamine neurotransmitter metabolism), which are implicated in the pathogenesis of anxiety and depression.10, 11, 12. The gene discussed is IL17A; the disease is depressive symptom measurement.