Multivariate logistic regression analysis revealed that TNF‐α (odds ratio [OR] (95% confidence interval [CI]) = 1.031 [1.007–1.056], P = 0.012), IL‐1β (OR [95% CI] = 1.376 [1.159–1.633], P < 0.001), marriage (single/divorced/widowed) status (OR [95% CI] = 2.086 [1.064–4.090], P = 0.032), diabetes (OR [95% CI] = 2.948 [1.181–7.360], P = 0.021), higher TNM stage (OR [95% CI] = 2.047 [1.344–3.117], P = 0.001), and longer duration after surgery (OR [95% CI] = 1.414 [1.080–1.852], P = 0.012) were independently correlated with elevated anxiety risk in NSCLC survivors (Table 2). This evidence concerns the gene IL1B and Anxiety.