Recently, emerging evidence has demonstrated that circ‐ZNF609 is differentially expressed in distinct cancers, such as RCC, CRC, NPC, GC, LC, HCC, prostate cancer, CC, glioma and other diseases such as RMS, HSCR, vascular dysfunction, glaucoma, CNV, neuropathic pain, DM1, DR and LN. The gene discussed is ZNF609; the disease is central nervous system cancer.