Excitingly, selected compounds that attenuated motor defects associated with loss of DJ-1β function also increased the viability of DJ-1-deficient human neuroblastoma cells subjected to OS conditions [34], thereby supporting the translatability of pharmacological studies carried out in Drosophila. The conservation of the BBB in flies increases the probability of encountering novel and relevant therapeutic compounds to treat PD and other human diseases [27, 35]. Here, PARK7 is linked to Parkinson disease.