As such, solid tumor growth is typically accompanied by angiogenesis and lymphangiogenesis via stimulation of VEGF receptor-1 (VEGFR-1), VEGFR-2, and VEGFR-3 on tumor-associated endothelial cells (TECs), subsequently improving energy metabolism, proliferation, and metastasis of tumor cells2. The gene discussed is FLT1; the disease is neoplasm.